NDLI: Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?

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Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?

Content Provider	Semantic Scholar
Author	Lemos, Hernani Pinto De Atallah, Alvaro Nagib
Copyright Year	2007
Abstract	CONTEXT AND OBJECTIVE The safety and efficacy of drug-eluting stents reduce the need for surgical revascularization. The objective of the present study was to investigate whether paclitaxel or rapamycin-eluting stent are effective in avoiding the need for coronary-artery bypass grafting. METHODS This was a systematic review of the literature using the methodology of the Cochrane Collaboration. The type of study considered was controlled randomized trials; the type of intervention was drug-eluting or bare-metal stents; and the main outcome investigated was coronary-artery bypass grafting. RESULTS The ten studies included in this systematic review did not show any statistically significant difference between the drug-eluting stents and the bare-metal stents with regard to the outcome of coronary-artery bypass grafting (confidence interval: 0.31 to 1.42). CONCLUSION The surgical revascularization rate was not reduced by the use of drug-eluting stents.
Starting Page	1
Ending Page	6
Page Count	6
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.scielo.br/pdf/spmj/v125n4/v125n4a10.pdf
PubMed reference number	17992397v1
Volume Number	125
Issue Number	4
Journal	Sao Paulo medical journal = Revista paulista de medicina
Language	English
Access Restriction	Open
Subject Keyword	Confidence Intervals Drug-Eluting Stents Paclitaxel Sirolimus Stent Device Component Stent, device Transplanted tissue bypass revascularization
Content Type	Text
Resource Type	Article

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