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CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8cc05113e
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hems, Edward S. Wagstaff, Ben A. Saalbach, Gerhard Field, Robert A. |
| Copyright Year | 2018 |
| Abstract | In the context of discovering and quantifying terminal alkyne-based natural products, here we report the combination of CuAAC click chemistry with LC-MS for the detection of polyether toxins (prymnesins) associated with harmful algal blooms. The added-value of the CuAAC-based approach is evident from our ability to detect novel prymnesin-like compounds in algal species with previously uncharacterised toxins. |
| Starting Page | 12234 |
| Ending Page | 12237 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c8cc05113e |
| PubMed reference number | 30311608 |
| Journal | Medline |
| Volume Number | 54 |
| Alternate Webpage(s) | https://ueaeprints.uea.ac.uk/68638/1/Published_manuscript.pdf |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c8/cc/c8cc05113e/c8cc05113e1.pdf |
| Journal | Chemical communications |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |