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The association between serum follicle-stimulating hormone levels and the success of microdissection testicular sperm extraction in patients with azoospermia.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yildirim, Mehmet Erol Koç, Akif Kaygusuz, Ikbal Cekmen Badem, Hüseyin Karatas, Omer Faruk Çimentepe, Ersin Unal, Doğan |
| Copyright Year | 2014 |
| Abstract | PURPOSE To evaluate the predictive power of luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, testicular biopsy histology and male age were evaluated with respect to the success of sperm retrieval in a microdissection testicular sperm extraction (microTESE) procedure, pregnancy and live birth rates. MATERIALS AND METHODS We examined the data of 131 infertile men with non-obstructive azoospermia, who have undergone microTESE operation. The men were classified into two groups based on serum follicle-stimulating hormone (FSH) levels ≤ 15 mIU/mL (group 1) and > 15 mIU/mL (group 2). RESULTS Group 1 consisted of 59 patients (mean age 36.2 ± 6.2 years) and group 2 consisted of 72 (mean age 38.8 ± 7.4 years) patients. Sperm retrieval and pregnancy rates were 66.1% and 16.9% in normal FSH group, respectively. These parameters were higher than those of men with FSH > 15 (43% and 8.3%, respectively). Only 128 patients had histopathological diagnosis. Sperm was retrieved from 12/30 (40%) patients with maturation arrest, 9/29 (31.03%) patients with seminiferous tubules atrophy, 14/40 (35%) patients with sertoli cell only syndrome and 13/13 (100%) of patients with hypospermatogenesis. There was no statistically significant difference in pathological diagnosis between pregnancy and live birth rates. CONCLUSION These results demonstrate that there is a significant difference with sperm retrieval, pregnancy rates and live birth rates comparing the FSH levels. Histopathological findings did not associate with successful microTESE, pregnancy rates and live birth rates. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://urologyjournal.org/index.php/uj/article/viewfile/2536/957 |
| PubMed reference number | 25194084v1 |
| Volume Number | 11 |
| Issue Number | 4 |
| Journal | Urology journal |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Anatomical maturation Birth Rate Classification Congenital absence of germinal epithelium of testes Fifty Nine Follicle Stimulating Hormone Gonadorelin Lung Diseases, Obstructive Non-obstructive azoospermia Oligospermia Ovarian Follicle Patients Pregnancy Rate Seminiferous tubule structure Sperm Retrieval Spermatozoa Cell Count Stimulation (motivation) Structure of sertoli cell Testicular Diseases Testicular Neoplasms Testosterone maturation arrest |
| Content Type | Text |
| Resource Type | Article |
