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Intraoperative assessment of tubules in predicting microdissection testicular sperm extraction outcome in men with Sertoli cell-only syndrome
| Content Provider | SAGE Publishing |
|---|---|
| Author | Yu, Yang Xi, Qi Wang, Ruixue Zhang, Hongguo Li, Leilei Zhu, Haibo Pan, Yuan Liu, Ruizhi |
| Copyright Year | 2018 |
| Abstract | ObjectiveThis study aimed to assess the value of measuring the tubule diameter during microdissection testicular sperm extraction (micro-TESE) in predicting outcomes in patients with Sertoli cell-only syndrome (SCOS).MethodsFifty-six consecutive patients with SCOS were included. Patients were classified into two groups on the basis of the diameter of seminiferous tubules measured against 5/0 surgical suture (≥100 µm or <100 µm).ResultsThe sperm retrieval rate (SRR) in men with a tubule diameter ≥100 µm was significantly lower than that in those with <100 µm (3.1% vs. 25.0%). The SRR from the contralateral testis in men with a tubule diameter ≥100 µm was lower than that in those with <100 µm (0% vs. 14.3%). Men with a tubule diameter ≥100 µm had a significantly larger testis and lower follicle-stimulating hormone levels than did men with <100 µm (8.1 ± 2.4 vs. 5.3±1.8 mL, 19.9 ± 9.7 vs. 25.9 ± 7.1 mIU/mL, respectively).ConclusionsThe diameter of tubules is a useful predictor for a successful SRR in men with SCOS. Intraoperative assessment of homogeneous large tubules allows some men to perform a limited (superficial) contralateral micro-TESE after no spermatozoa are initially identified. |
| Related Links | https://journals.sagepub.com/doi/pdf/10.1177/0300060518809257?download=true |
| Starting Page | 722 |
| Ending Page | 729 |
| Page Count | 8 |
| ISSN | 03000605 |
| Issue Number | 2 |
| Volume Number | 47 |
| Journal | Journal of International Medical Research (IMR) |
| e-ISSN | 14732300 |
| DOI | 10.1177/0300060518809257 |
| Language | English |
| Publisher | Sage Publications UK |
| Publisher Date | 2018-11-15 |
| Publisher Place | London |
| Access Restriction | Open |
| Rights Holder | © The Author(s) 2018 |
| Subject Keyword | Nonobstructive azoospermia seminiferous tubule diameter microdissection testicular sperm extraction microdissection Sertoli cell-only syndrome sperm retrieval |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry (medical) Cell Biology Biochemistry |
