Loading...
Please wait, while we are loading the content...
Similar Documents
Low- vs. Middle-dose Total Skin Electron Beam Therapy for Mycosis Fungoides: An Efficiency-based Retrospective Survey of Skin Response.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Taverniers, A. Du-Thanh, Aurélie Charissoux, Marie Kerr, Christine Dereure, Olivier |
| Copyright Year | 2019 |
| Abstract | Optimal doses of total skin electron beam therapy for mycosis fungoides remain to be established. Clinical efficiency and adverse effects of middle-dose (25 Gy) vs. low-dose (10-12 Gy) total skin electron beam therapy were retrospectively compared in a series of 14 and 12 mycosis fungoides, respectively. Overall skin response rate was 96.2% (92.9% middle-dose and 100% low-dose; not significant (NS)). Overall complete and partial skin response rates were 57.7% (42.9% middle-dose and 75% low-dose; NS) and 38.5% (50% middle-dose and 25% low-dose; NS), respectively. All responding patients relapsed after an overall median time of 5 months (7 months middle-dose vs. 4 months low-dose; p = 0.164, NS). Tolerance was equally fair in both groups, with only grade 1 and 2 adverse events observed in 100% vs. 66.7% of patients in middle-dose and low-dose groups (NS). Although no significant difference was observed, middle-dose protocol may be recommended owing to a longer relapse-free survival for a similar tolerance. |
| Starting Page | 544 |
| Ending Page | 550 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| DOI | 10.2340/00015555-3124 |
| PubMed reference number | 30653243 |
| Journal | Medline |
| Volume Number | 99 |
| Issue Number | 6 |
| Journal | Acta dermato-venereologica |
| Alternate Webpage(s) | https://www.medicaljournals.se/acta/content_files/files/pdf/99/6/5392.pdf |
| Alternate Webpage(s) | https://doi.org/10.2340/00015555-3124 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
