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Instability of Doppler cerebral blood flow in monochorionic twins.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Degani, Shimon Leibovitz, Zvi Shapiro, Israel Gonen, Ron Ohel, Gonen |
| Copyright Year | 2006 |
| Abstract | OBJECTIVE The purpose of this study was to evaluate Doppler flow velocity changes in cerebral vessels of monochorionic twins with twin-twin transfusion syndrome (TTTS). METHODS Repeated Doppler umbilical and cerebral blood flow studies were performed in 7 twin pairs with TTTS. Eight monochorionic twin pairs and 11 dichorionic twin pairs served as control groups. The following Doppler parameters were assessed: umbilical artery pulsatility index (PI), middle cerebral artery (MCA) PI, cerebroplacental ratio, delta PI between the umbilical artery and MCA, and peak systolic velocity (PSV) in the MCA. RESULTS Significant variations in PSV in the MCA and cerebral indices were found in the study group of monochorionic twins with TTTS. Periods of high PSV with low PI in the MCA were followed by lower PSV in the same fetus. Repeated measurements in the comparison groups were stable without significant variations. The delta cerebroplacental ratio was significantly higher in the study group (0.38 versus 0.09 and 0.19 in the comparison groups; P < .02). CONCLUSIONS Significant changes in Doppler flow velocity and indices suggest instability of cerebral blood flow with episodes of "hyperperfusion" in monochorionic twins with TTTS. Further studies are needed to elucidate the relationship of these transient changes to neurologic sequelae in the neonate. |
| Starting Page | 73 |
| Ending Page | 83 |
| Page Count | 11 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.jultrasoundmed.org/content/25/4/449.full.pdf |
| PubMed reference number | 16567433v1 |
| Volume Number | 25 |
| Issue Number | 4 |
| Journal | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | 20-Methylcholanthrene Blood Vessel Body mass index Cerebrovascular Circulation Cerebrovascular system Delta aminolevulinate/Creatinine:SRto:24H:Urine:Qn Fetus Fetus-to-fetus placental transfusion syndrome Heart Failure, Systolic Infant, Newborn Sequela of disorder Structure of cerebral artery Structure of middle cerebral artery Structure of umbilical artery Umbilicus (Anatomy) nervous system disorder |
| Content Type | Text |
| Resource Type | Article |
