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Evaluation of Live Attenuated Shigella dysenteriae Type 1 Strain as a Candidate Vaccine
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chaleshtori, Salehi |
| Copyright Year | 2012 |
| Abstract | Aim: This study aimsto detect the ipaDplasmid inShigella dysenteriae type 1 and evaluatethe invasive ability of a live, attenuated Shigella dysenteriae type 1 generated from deletion of the ipaDplasmid. The attenuated strain was tested in guinea pigs. Materials and Methods: We performed biochemical and antibody tests in addition to PCR analysis, t o identify the strain and serotype of an isolatedShigellastrain.The plasmid version of theipaDgene was recognized.We generated a l ive, attenuated |
| Starting Page | 28 |
| Ending Page | 35 |
| Page Count | 8 |
| File Format | PDF HTM / HTML |
| Volume Number | 1 |
| Alternate Webpage(s) | http://teb.police.ir/teb/article-1-66-fa.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |