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The response of arginine vasopressin and plasma renin to postural change in normal man, with observations on syncope.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Davies, Roy Slater, J. D. H. Forsling, Mary L. Payne, Nancy |
| Copyright Year | 1976 |
| Abstract | 1. Fourteen mildly hydropenic normal volunteers were slowly tilted at a constant rate from the horizontal to the 85 degrees head-up position in order to study the interrelationship between plasma arginine vasopressin concentration, plasma renin activity and the change of plasma volume. 2. Nine subjects did not develop vaso-vagal symptoms and were studied for 45-60 min. Arginine vasopressin rose biphasically in all subjects: a small initial rise, which was seen at 3 min and persisted for 30 min, was followed by a striking rise between 30 and 45 min, when the fall of plasma volume had reached its maximum (17%). 3. Plasma renin activity reached a maximum at 30 min but fell by 45 min, as plasma concentration of arginine vasopressin rose. 4. Five subjects developed vaso-vagal symptoms 4-24 min after reaching 85 degrees when the study was terminated. A striking increase of arginine vasopressin concentration was seen within 4 min of syncope, but there was no change of plasma osmolality, cortisol concentration or renin activity. |
| File Format | PDF HTM / HTML |
| DOI | 10.1042/cs0510267 |
| PubMed reference number | 963956 |
| Journal | Medline |
| Volume Number | 51 |
| Issue Number | 3 |
| Alternate Webpage(s) | http://www.clinsci.org/content/ppclinsci/51/3/267.full.pdf |
| Alternate Webpage(s) | https://doi.org/10.1042/cs0510267 |
| Journal | Clinical science and molecular medicine |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
