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Plasma-arginine-vasopressin Response to Insulin-induced Hypoglycæmia
| Content Provider | Semantic Scholar |
|---|---|
| Author | Baylis, Peter H. Heath, Derek A. |
| Copyright Year | 1977 |
| Abstract | Insulin-induced hypoglycaemia caused a threefold rise in plasma-arginine-vasopressin concentration (to 4-36 +/- 0-77 pmol/1) in ten subjects who had normal posterior-pituitary function. Plasma-arginine vasopressin reached a peak 30 min after injection of insulin. Plasma concentrations of arginine vasopressin obtained with hypoglycaemia were similar to those achieved after overnight dehydration for 14-16 h. No rise in plasma-arginine-vasopressin was observed in three patients with cranial diabetes insipidus in whom severe hypoglycaemia developed after insulin infusion. It is suggested that the measurement of arginine vasopressin during insulin-induced hypoglycaemia may be a useful clinical test of posterior-pituitary function. |
| Starting Page | 428 |
| Ending Page | 430 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/S0140-6736(77)90610-9 |
| PubMed reference number | 70644 |
| Journal | Medline |
| Volume Number | 310 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/S0140673677906109 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/S0140673677906109?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/S0140-6736%2877%2990610-9 |
| Journal | The Lancet |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |