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Neoadjuvant chemotherapy for stage IIIA-N2 non-small cell lung cancer.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Marinis, Filippo De Gebbia, V. Petris, Luigi De |
| Copyright Year | 2005 |
| Abstract | Neoadjuvant chemotherapy in potentially resectable stage IIIA-N2 non-small cell lung cancer (NSCLC) has become standard of treatment in the last years. Two randomised pioneer phase III trials conducted with second generation platinum combinations had demonstrated an advantage in survival of induction chemotherapy followed by surgery versus surgery alone. Subsequently, a wide number of phase II studies with third generation platinum-based doublets or triplets have increased the evidence of the activity as well as the good tolerability of this approach. Nowadays, the main topics of ongoing clinical research are to assess the role of induction chemotherapy in early stage disease, and the role of induction radiotherapy, as well as definite chemo-radiotherapy in stage IIIA NSCLC. This report review these issues and focuses on current treatment options for resectable stage IIIA-N2 NSCLC. |
| File Format | PDF HTM / HTML |
| DOI | 10.1093/annonc/mdi920 |
| PubMed reference number | 15923411 |
| Journal | Medline |
| Volume Number | 16 |
| Alternate Webpage(s) | https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/annonc/16/suppl_4/10.1093/annonc/mdi920/2/mdi920.pdf?Expires=1493132191&Key-Pair-Id=APKAIUCZBIA4LVPAVW3Q&Signature=It8emuK~FCKhy3TpJDre0HEXuPO6jvVwVUnv1SSEQOQlmwHso-uaTJhIy~6MadFyHXqhKvSDEFNywiCnohm-IvKILww1pQbcOzlxae2JDqwSf78XEb8ep~HlCpqJp~erxoAUNv~nLF5cKRuaAEEKwewPD~luqfp3qp~~w1N-dVbX-pbaBNd5AW~zZ1vrr4DlMp0zQQilYPHt8sDIlLGEnsOg5eYidRAT4B5EsmdNN8csUUI7zM3~suhstzxgWZXschXxMrsKZXuOb9f8ERrVpVi2YvahxhsuBF3CI2D2YslZVjKCYBu8NVJxZLfAKc52774QF6sjtssPyd1BlelK6w__ |
| Alternate Webpage(s) | https://doi.org/10.1093/annonc%2Fmdi920 |
| Journal | Annals of oncology : official journal of the European Society for Medical Oncology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |