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Advances in multimodal treatment for stage IIIA-N2 non-small cell lung cancer.
| Content Provider | Europe PMC |
|---|---|
| Author | Montemuiño Muñiz, Sara Marcos Sánchez, Soraya Calzas Rodríguez, Julia Losada Vila, Beatriz Llorente Herrero, Esther Hisado Díaz, María Dolores Valeri-Busto González, Victoria Taboada Valladares, Begoña Vaquero Barrón, Blanca Marcos Jimenez, Francisco José Amor Alonso, Sergio Moradiellos, Javier Rodríguez de Dios, Núria Couñago, Felipe |
| Copyright Year | 2021 |
| Abstract | Background and Aim:In Stage IIIA-N2 non-small cell lung cancer (NSCLC), the accuracy of combinedpositron-emission tomography/computed tomography imaging (PET-CT), togetherwith mediastinal staging techniques, has led to a wide range of challengingclinical scenarios in terms of therapeutic management. Concurrentchemoradiotherapy followed by consolidation immunotherapy remains thestandard of care. In patients with potentially-resectable disease, surgeryplays an important role in multimodal therapy. The introduction of targetedtherapies and immune-checkpoint inhibitors has revolutionized multimodaltreatment. In the present article, we review current treatment options andfuture trends in stage IIIA-N2 NSCLC.Relevance for Patients:This article provides insight into the current status of multimodal treatmentfor NSCLC to support decision-making in routine clinical practice. |
| Related Links | https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8177852&blobtype=pdf |
| ISSN | 23826533 |
| Journal | Journal of Clinical and Translational Research [J Clin Transl Res] |
| Volume Number | 7 |
| PubMed Central reference number | PMC8177852 |
| Issue Number | 2 |
| PubMed reference number | 34104821 |
| e-ISSN | 2424810X |
| Language | English |
| Publisher | Whioce Publishing Pte. Ltd. |
| Publisher Date | 2021-04-16 |
| Access Restriction | Open |
| Rights License | This is an open-access article distributed under the terms of theCreative Commons Attribution License (CC BY-NC-ND 4.0), which permitsunrestricted use, distribution, and reproduction in any medium, provided theoriginal work is properly cited. Copyright: © Whioce Publishing Pte.Ltd. |
| Subject Keyword | chemoradiation immunotherapy neoadjuvant treatment non-small cell lung cancer stage IIIA surgery |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |