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Invited Review Annonaceous Acetogenins: Recent Progress
| Content Provider | Semantic Scholar |
|---|---|
| Author | Alali, Q. Liu, Xiao-Xi McLaughlin, Jerry |
| Copyright Year | 1999 |
| Abstract | The Annonaceous acetogenins are promising new antitumor and pesticidal agents that are found only in the plant family Annonaceae. Chemically, they are derivatives of long-chain fatty acids. Biologically, they exhibit their potent bioactivities through depletion of ATP levels via inhibiting complex I of mitochondria and inhibiting the NADH oxidase of plasma membranes of tumor cells. Thus, they thwart ATP-driven resistance mechanisms. This review presents the progress made in the chemistry, biology, and development of these compounds since December 1995. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://graviolacancers.com/wp-content/uploads/2013/12/acetogenins1999.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |