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Off-axis integrated cavity output spectroscopy with a mid-infrared interband cascade laser for real-time breath ethane measurements.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Parameswaran, Krishnan R. Rosen, David I. Allen, Mark G. Ganz, Alan M. Risby, Terence H. |
| Copyright Year | 2009 |
| Abstract | Cavity-enhanced tunable diode laser absorption spectroscopy is an attractive method for measuring small concentrations of gaseous species. Ethane is a breath biomarker of lipid peroxidation initiated by reactive oxygen species. A noninvasive means of quickly quantifying oxidative stress status has the potential for broad clinical application. We present a simple, compact system using off-axis integrated cavity output spectroscopy with an interband cascade laser and demonstrate its use in real-time measurements of breath ethane. We demonstrate a detection sensitivity of 0.48 ppb/Hz(1/2). |
| File Format | PDF HTM / HTML |
| DOI | 10.1364/AO.48.000B73 |
| Alternate Webpage(s) | http://www.psicorp.com/pdf/library/SR-1341.pdf |
| PubMed reference number | 19183584 |
| Alternate Webpage(s) | https://doi.org/10.1364/AO.48.000B73 |
| Journal | Medline |
| Volume Number | 48 |
| Issue Number | 4 |
| Journal | Applied optics |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
