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Antioxidant, cytotoxic and thrombolytic activity of leaves of Kalanchoe pinnata (LAM.) PERS.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chowdhury, Kazi Ashfak Ahmed Huq, Mohammed Emranul Ali, Sekendar Huq, Irfanul Royhan, Mohammad Johir Adnan Chy, Nazim Uddin Kabir, Imtiazul Auniq, Reedwan Bin Jafar Uddin, Rakib Zaman, Raihan Uz |
| Copyright Year | 2016 |
| Abstract | The study was aimed to evaluate the, antioxidant, cytotoxic and thrombolytic activity of ethanol extract of the leaves of Kalanchoe pinnata. In vitro antioxidant activity of extract was studied using DPPH radical scavenging, reducing power determination assays. The antioxidant activity of the extracts was found promising. The reducing powers of this crude extract increase with the increase of concentration. IC50 values of DPPH scavenging activity was 282.136±0.46μg/ml. The cytotoxic activity of crude extract was determined using brine shrimp lethality bioassay and LC50 values of the sample was 51.88 ± 0.52μg/ml whereas for standard vincristine sulphate was 8.50 ± 0.16μg/ml as a positive control. The plant’s extract showed (15.73 ±1.31%) clot lytic as compared to standard streptokinase’s (30.26% ± 0.67) clot lytic activity in case of thrombolysis assay |
| Starting Page | 309 |
| Ending Page | 315 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Volume Number | 5 |
| Alternate Webpage(s) | http://www.phytojournal.com/archives/2016/vol5issue4/PartD/5-4-13-617.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |