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GC-MS Analysis, Free-Radical-Scavenging and Insecticidal Activities of Essential Oil of Scrophularia oxysepala Boiss.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Pasdaran, Ardalan Nahar, Lutfun Asnaashari, Solmaz Sarker, Satyajit Dey Delazar, Abbas |
| Copyright Year | 2013 |
| Abstract | Scrophularia oxysepala Boiss. is endemic to western and central regions of Iran, and belongs to the genus Scrophularia (family: Scrophulariaceae), which has long been used in traditional medicines. In the present work, chemical composition of the essential oil of the aerial parts of this species was analyzed. Methods: The air-dried ground aerial parts of S. oxysepala were subjected to hydro-distillation. The resulting oil was analyzed, for the first time, by the gas chromatography/mass spectrometry (GC-MS) and gas chromatography/flame ionization detection (GC-FID). Free-radical-scavenging activity of the essential oil was determined by the DPPH assay. Adults of Oryzeaphilus mercator were used for contact toxicity insecticidal assay. Results: A total yield of 0.1 ml of essential oil per 100 g of plant dry mass was obtained, and 15 compounds were identified, representing 91.2% of total oil. The essential oil was characterized by a high content of aromatic compounds and phytol. The main constituents were phytol (25.3%), methyl benzyl alcohol (9.3%), dehydrodieugenol (6.7%), methyl benzaldehyde (5.3%) and eugenol (1.3%). The low level of free-radical-scavenging activity of the essential oil was demonstrated by the RC50 value of 1.852mg/ml, and the insecticidal activity was also found to be low. Conclusion: The insecticidal activity of this essential oil was not remarkable, but was time and concentration-dependent. The low free-radical-scavenging activity was probably due to its low percentage of phenolic compounds |
| Starting Page | 1 |
| Ending Page | 5 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| Volume Number | 19 |
| Alternate Webpage(s) | https://journals.tbzmed.ac.ir/PHARM/Manuscript/PHARM-19-1.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |