NDLI: Association between Pri-miR-34b/c rs4938723 polymorphism and bladder cancer risk

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Association between Pri-miR-34b/c rs4938723 polymorphism and bladder cancer risk

Content Provider	Semantic Scholar
Author	Hashemi, Mohammad Hasanpour, Vahed Danesh, H. Sopariwala Bizhani, Fatemeh Narouie, Behzad
Copyright Year	2018
Abstract	Several studies examined the impact of miR-34b/c rs4938723 polymorphism and cancer risk, but the findings are inconsistent. However, no study has been conducted to inspect the impact of miR-34b/c polymorphism on bladder cancer. This study aimed to assess possible association between rs4938723 polymorphism and bladder cancer risk. This case-control study was done on 136 pathologically proven bladder cancer patients and 144 controls. Genotyping of Pri-miR-34b/c rs4938723 polymorphism was achieved by using the polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method. Our findings did not show any statistically significant differences in genotype and allele frequencies between bladder cancer and controls. Larger sample sizes with diverse ethnicities are required to validate our findings.
Starting Page	24
Ending Page	29
Page Count	6
File Format	PDF HTM / HTML
DOI	10.7555/JBR.31.20170044
PubMed reference number	30190447
Journal	Medline
Volume Number	33
Alternate Webpage(s)	http://www.jbr-pub.org.cn/fileSWYXYJZZYWB/journal/article/swyxyjzzywb/2019/1/PDF/jbr-33-1-24.pdf
Journal	Journal of biomedical research
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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