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Rapid Determination of Enantiomeric Excess via NMR Spectroscopy: A Research-Informed Experiment
| Content Provider | Semantic Scholar |
|---|---|
| Author | Fossey, John S. Anslyn, Eric V. Brittain, William D. G. Bull, Steven D. Chapin, Brette M. Duff, Cécile S. Le James, Tony D. Lees, Glenn Lim, Stephanie Lloyd, Jennifer Anne Manville, Charles V. Payne, Daniel T. Roper, Kimberley A. |
| Copyright Year | 2017 |
| Abstract | An undergraduate chemistry experiment that draws from primary research is described. The experiment exploits chiral supramolecular assemblies for the determination of enantiomeric excess by 1H NMR spectroscopy. This report describes the delivery of the experiment to a cohort of students, and as a result of feedback from those involved, an optimized protocol is presented. Particular care has been taken to facilitate ready adoption in other institutions by providing comprehensive teaching support materials as well as technical guidance for supporting the experiment. |
| Starting Page | 79 |
| Ending Page | 84 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1021/acs.jchemed.6b00355 |
| Volume Number | 94 |
| Alternate Webpage(s) | https://research.birmingham.ac.uk/portal/files/33276574/acs_2Ejchemed_2E6b00355.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |