NDLI: Angiographic patterns of restenosis after sirolimus-eluting stent implantation.

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Angiographic patterns of restenosis after sirolimus-eluting stent implantation.

Content Provider	Semantic Scholar
Author	Kitahara, Hideki Kobayashi, Yoshio Takebayashi, Hideo Nakamura, Yoshitake Kuroda, Nakabumi Miyazaki, Akira Haruta, Seiichi Komuro, Issei
Copyright Year	2009
Abstract	BACKGROUND Large-scale randomized trials demonstrate a high proportion of focal restenosis after drug-eluting stent (DES) implantation. On the other hand, recent reports have shown that in real-world practice a significant proportion of the restenosis is non-focal when DESs are used in unselected lesions. The present study evaluated angiographic patterns of restenosis after sirolimus-eluting stent (SES) implantation in Japan. METHODS AND RESULTS Angiographic restenosis patterns of all consecutive restenotic lesions (n=124) after SES implantation were evaluated and classified according to the following scheme: focal (10 mm within the stent), proliferative (restenosis >10 mm in length extending outside the stent), and occlusive. There were 98 focal (79.0%), 15 diffuse (12.1%), and 5 proliferative restenoses (4.0%) and 6 total occlusions (4.8%). Focal intrastent restenosis was most dominant (42.7%). Proximal edge restenosis occurred in 22 lesions (17.7%). Multivariate analysis demonstrated diabetes mellitus (P<0.01) as an independent predictor of non-focal restenosis. CONCLUSIONS Focal restenosis is predominant after SES implantation in real-world practice in Japan.
Starting Page	2455
Ending Page	2460
Page Count	6
File Format	PDF HTM / HTML
Alternate Webpage(s)	https://www.jstage.jst.go.jp/article/circj/73/3/73_CJ-08-0720/_pdf
PubMed reference number	19151505v1
Volume Number	73
Issue Number	3
Journal	Circulation journal : official journal of the Japanese Circulation Society
Language	English
Access Restriction	Open
Subject Keyword	Classification Diabetes Mellitus Drug Screening Assays, Antitumor Drug-Eluting Stents Graft Occlusion, Vascular Obstruction Sirolimus Stent Device Component Stent, device restenosis
Content Type	Text
Resource Type	Article

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