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Organocatalytic enantioselective indole alkylations of alpha,beta-unsaturated ketones.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chen, Wei Wu, Yong Ding, Li-Sheng Chen, Ying-Chun |
| Copyright Year | 2007 |
| Abstract | The C3-selective enantioselective Michael-type Friedel-Crafts alkylations of indoles with nonchelating alpha,beta-unsaturated alkyl ketones, catalysed by a chiral primary amine derived from natural cinchonine, were investigated. The reactions, in the presence of 30 mol% catalyst, were smoothly conducted at 0 to -20 degrees C. Moderate to good ee (47-89%) has been achieved. |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/B616504D |
| PubMed reference number | 17315068 |
| Journal | Medline |
| Volume Number | 5 |
| Issue Number | 5 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/ob/b6/b616504d/b616504d.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/B616504D |
| Journal | Organic & biomolecular chemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |