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On the origin of substance P and glutamic acid decarboxylase (GAD) in the substantia nigra
| Content Provider | Semantic Scholar |
|---|---|
| Author | Brownstein, Michael J. Mroz, Edmund A. Tappaz, Marcel L. Leeman, Susan E. |
| Copyright Year | 1977 |
| Abstract | Knife cuts in the frontal plane separating the anterior part of the caudate-putamen from the globus pallidus resulted in marked decreases in substances P levels in the reticular part of the substantia nigra. More caudal knife cuts were required in order to effect maximal decreases in nigral glutamic acid decarboxylase levels. Thus, there is a clear anatomical dissociation between the striatal neurons which project to the reticular part of the substantia nigra and which contain SP, and the more caudally located GAD-containing striatal and pallidal neurons, all of which travel through the globus pallidus on their way to the substantia nigra. |
| Starting Page | 315 |
| Ending Page | 323 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0006-8993(77)91034-4 |
| PubMed reference number | 922480 |
| Journal | Medline |
| Volume Number | 135 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/0006899377910344 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/0006899377910344?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0006-8993%2877%2991034-4 |
| Journal | Brain Research |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
