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Turbulence in human intracranial saccular aneurysms.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Ferguson, Gary G. |
| Copyright Year | 1970 |
| Abstract | ✓ Preliminary experiments with glass model bifurcation aneurysms demonstrated that turbulent flow pattern occurs in the sac of an aneurysm at a low flow rate (critical Reynolds number, 400 ± 10 S.E.M.). A prediction that flow is turbulent in the sac of human intracranial saccular aneurysms was confirmed in a clinical study. Bruits, indicative of turbulence, were recorded with a phonocatheter from the sacs of 10 out of 17 intracranial aneurysms exposed at surgery where the mean arterial pressures were above 50 mm Hg. The amplitude of the bruits varied with the pressure. All of the patients in whom no bruit was found had profound Arfonad hypotension at the time of recording. Turbulence causes vibration in the wall of a vessel. This vibration produces and accelerates degenerative changes in vascular tissue by a process similar to the structural fatigue of metals by vibration. The author proposes that the turbulent blood flow within an aneurysm contributes to the degeneration of the elastica, and the producti... |
| File Format | PDF HTM / HTML |
| DOI | 10.3171/jns.1970.33.5.0485 |
| PubMed reference number | 5479489 |
| Journal | Medline |
| Volume Number | 33 |
| Issue Number | 5 |
| Alternate Webpage(s) | https://thejns.org/downloadpdf/journals/j-neurosurg/33/5/article-p485.pdf |
| Alternate Webpage(s) | https://doi.org/10.3171/jns.1970.33.5.0485 |
| Journal | Journal of neurosurgery |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
