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Susceptibilities of 177 penicillin-susceptible and -resistant pneumococci to FK 037, cefpirome, cefepime, ceftriaxone, cefotaxime, ceftazidime, imipenem, biapenem, meropenem, and vancomycin.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Spangler, Samantha Jacobs, Michael R. Appelbaum, Peter C. |
| Copyright Year | 1994 |
| Abstract | MICs of six extended-spectrum cephalosporins (cefotaxime, ceftriaxone, ceftazidime, FK 037, cefpirome, cefepime), three carbapenems (imipenem, meropenem, biapenem), and vancomycin for 49 penicillin-susceptible (S), 77 penicillin intermediate-resistant (I), and 51 penicillin-resistant (R) pneumococci were determined by agar dilution. Compared with ceftazidime (MICs for 90% of strains tested [MIC90s] of 2.0, 16.0, and 16.0 micrograms/ml for S, I, and R strains, respectively), all other cephalosporins yielded lower MICs (MIC90s of 0.06 to 0.125, 0.5 to 1.0, and 1.0 to 2.0 micrograms/ml against S, I, and R strains, respectively). All three carbapenems were very active, with MIC90s, even for R strains, of < or = 1.0 micrograms/ml. All strains were susceptible to vancomycin (MIC90 of 0.5 micrograms/ml). |
| Starting Page | 898 |
| Ending Page | 900 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://aac.asm.org/content/38/4/898.full.pdf |
| PubMed reference number | 8031069v1 |
| Volume Number | 38 |
| Issue Number | 4 |
| Journal | Antimicrobial agents and chemotherapy |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Agar Carbapenems Cefotaxime Ceftazidime Ceftriaxone Cephalosporins Disease susceptibility Forty Nine Imipenem Penicillins Vancomycin biapenem cefepime cefpirome meropenem penicillin G procaine |
| Content Type | Text |
| Resource Type | Article |
