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Multicenter comparison of in vitro activities of FK-037, cefepime, ceftriaxone, ceftazidime, and cefuroxime.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Washington, John A. Jones, Ronald Gerlach, E. Hugh Murray, Patrick R. Allen, Stephen D. Knapp, Cindy C. |
| Copyright Year | 1993 |
| Abstract | In a multicenter study, the MICs of FK-037 for 90% of the strains tested (MIC90s) were < or = 1 microgram/ml for members of the family Enterobacteriaceae other than Citrobacter freundii, Enterobacter spp., and Serratia marcescens. Activity against Pseudomonas aeruginosa was variable, with a MIC50 and a MIC90 of 4 and 32 micrograms/ml, respectively. Relative to cefepime, however, FK-037 was less active against ceftazidime-resistant isolates of Enterobacter cloacae. The MIC90 of FK-037 for methicillin-resistant staphylococci was > 16 micrograms/ml. |
| File Format | PDF HTM / HTML |
| DOI | 10.1128/AAC.37.8.1696 |
| Alternate Webpage(s) | http://aac.asm.org/content/37/8/1696.full.pdf |
| PubMed reference number | 8215286 |
| Alternate Webpage(s) | https://doi.org/10.1128/AAC.37.8.1696 |
| Journal | Medline |
| Volume Number | 37 |
| Issue Number | 8 |
| Journal | Antimicrobial agents and chemotherapy |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |