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Maturation of digestive function is retarded and plasma antioxidant capacity lowered in fully weaned low birth weight piglets.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Michiels, Joris Vos, Maartje De Missotten, Joris Ovyn, Anneke Smet, Stefaan De Ginneken, Christa J. Van |
| Copyright Year | 2013 |
| Abstract | The digestive function of low birth weight (LBW) pigs post-weaning has been poorly studied. Therefore, newborns from eleven hyperprolific sows were weighed, weaned at 27·2 d and fed a starter diet until sampling. Sampling was done between 18 and 28 d post-weaning. An LBW piglet (n 19) was defined as a piglet having a birth weight less than 1 kg and less than the lower quartile of litter birth weights. Normal birth weight (NBW) piglets (n 13) were having a birth weight close to the mean litter birth weight. For each piglet, eighty-eight variables were determined. Data were analysed with linear models with type of piglet and litter as predictors. A principal component analysis was performed to determine the most important discriminating variables. In the LBW pig, the development of the digestive tract post-weaning was delayed: lower small-intestinal weight:length ratio due to a thinner tela submucosa and tunica muscularis and a higher secretory capacity, both in the distal jejunum. These observations might be a consequence of lower circulating insulin-like growth factor-1 (IGF-1) concentrations (126 (se 10·0) v. 158 (se 12·0) ng/ml for LBW and NBW, respectively) and a lower density of IGF-1 receptors in the proximal small intestine. Additionally, the plasma antioxidant capacity was lower for the LBW pig. Taken together, in the LBW piglet, the normal gut maturation post-weaning was retarded and this did not seem to be related to the weaning transition as such. |
| Starting Page | 65 |
| Ending Page | 75 |
| Page Count | 11 |
| File Format | PDF HTM / HTML |
| DOI | 10.1017/S0007114512000670 |
| PubMed reference number | 22470197 |
| Journal | Medline |
| Volume Number | 109 |
| Issue Number | 1 |
| Alternate Webpage(s) | https://www.cambridge.org/core/services/aop-cambridge-core/content/view/A28CA7011B792EA3274D959CE3AD670E/S0007114512000670a.pdf/maturation_of_digestive_function_is_retarded_and_plasma_antioxidant_capacity_lowered_in_fully_weaned_low_birth_weight_piglets.pdf |
| Alternate Webpage(s) | https://doi.org/10.1017/S0007114512000670 |
| Journal | The British journal of nutrition |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
