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Angiographic and histologic consequences of laser thermal angioplasty: comparison with balloon angioplasty.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sanborn, Timothy A. Haudenschild, Christian C. Garber, Gary R. Ryan, Thomas James Faxon, David P. |
| Copyright Year | 1987 |
| Abstract | The angiographic and histologic consequences of laser thermal angioplasty were examined and compared with those of conventional balloon angioplasty in an atherosclerotic rabbit iliac artery preparation immediately and 4 weeks after the procedure. Nineteen vessels in 13 rabbits underwent either laser thermal or balloon angioplasty in random order. Laser thermal angioplasty was performed in a total of nine vessels with either a 1.5 or 2.0 mm laser-heated metallic-capped fiber by delivery of 6 or 8 W, respectively, of argon laser energy for 5 sec duration during continuous advancement through the stenosis. Balloon angioplasty was performed in a total of 10 stenotic lesions with a 2.5 mm balloon catheter. The immediate enlargement of the angiographic luminal diameters was similar for both procedures: from 1.0 +/- 0.2 to 1.9 +/- 0.2 mm for laser thermal angioplasty vs 1.0 +/- 0.1 to 2.0 +/- 0.2 mm for balloon angioplasty. However, 4 weeks later the vessels treated with laser thermal angioplasty had less restenosis, defined as a 20% or greater reduction in luminal diameter (two of nine vessels [22%] vs 10 of 10 vessels [100%]; p less than .001), and a significantly larger mean luminal diameter (1.6 +/- 0.5 vs 1.0 +/- 0.4 mm) than those treated with conventional balloon angioplasty (p less than .02). Histologic examination 4 weeks after the procedure revealed less fibrocellular proliferation after laser thermal angioplasty, whereas those vessels treated with balloon angioplasty demonstrated evidence of prior fracture and dissection of the vessel wall with more of a fibrocellular proliferative response.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Starting Page | 11 |
| Ending Page | 15 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://circ.ahajournals.org/content/circulationaha/75/6/1281.full.pdf?download=true |
| Alternate Webpage(s) | http://circ.ahajournals.org/content/circulationaha/75/6/1281.full.pdf |
| PubMed reference number | 2952375v1 |
| Volume Number | 75 |
| Issue Number | 6 |
| Journal | Circulation |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Angioplasty Angioplasty, Balloon Angioplasty, Balloon, Coronary Argon Blood Vessel Bone structure of ilium Diameter (qualifier value) Histological Techniques Hypertrophy Large Obstructive Ureterocele Phenobarbital Stenosis Tissue fiber Vascular calcification restenosis |
| Content Type | Text |
| Resource Type | Article |
