Loading...
Please wait, while we are loading the content...
Similar Documents
Quantification of microvascular leakage in malignant glioma and solitary brain metastasis using dynamic bolus tracking susceptibility perfusion MR imaging
| Content Provider | Semantic Scholar |
|---|---|
| Author | Cha, Soonmee Lupo, Janine M. Sadarangani, Pooja Nelson, Sarah J. Dillon, William |
| Copyright Year | 2004 |
| Abstract | FOV so that the observed signal changes had sufficient signal to noise ratio to be analyzed reliably on a voxel by voxel basis. The T2* signal intensity time curve, S(t), was converted to relative concentration using the relationship C(t) ~ -ln(S(t)/S0), where S0 is the average pre-contrast signal intensity baseline. Peak height and percent recovery of the post bolus signal from the peak were calculated for each voxel within the entire T2 lesion (T2L), contrast enhancing lesion (CEL), and nonenhancing peri-tumoral lesion (T2L-CEL). Peak height values were normalized to the peak of a model curve function derived from normal appearing brain based on histogram analysis of the pre-contrast echo planar images. Voxels with peak height values greater than twice the model curve were classified as having abnormal peak height (aPH). Regions with no signal drop (NSD), as defined by a flat signal on the time series data, were excluded from the calculations. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://cds.ismrm.org/ismrm-2004/Files/001980.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
