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A second encephalitogenic PLP epitope for SJL mice
| Content Provider | Semantic Scholar |
|---|---|
| Author | Greer, Judith M. Kuchroo, Vijay K. Sobel, Raymond A. Lees, Marjorie B. |
| Copyright Year | 1993 |
| Abstract | as little as 30 min of exposure to mitogen, lntracellular cAMP levels were relatively increased when exposed to a BAR agonist (10 5 M isoproterenol) by 129_+ 22% after mitogen activation compared to 67 + 17% in controls. There was no change in BAR K d after mitogen activation. These data indicate that BAR expression is upregulated after activation and contributes to an increase in cAMP. Further studies are ongoing to investigate the intracellular signals mediating the changes in BAR expression. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0165-5728(93)90108-B |
| Volume Number | 43 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/016557289390108B |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/016557289390108B?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0165-5728%2893%2990108-B |
| Journal | Journal of Neuroimmunology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |