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Correlation of anthropometric indicators for identifying insulin sensitivity and resistance.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Matos, Lívia Nascimento De Giorelli, Guilherme De Vieira Dias, Cristiane Bitencourt |
| Copyright Year | 2011 |
| Abstract | CONTEXT AND OBJECTIVES Early detection of reduced insulin sensitivity (IS) and insulin resistance (IR) is desirable. The aim here was to evaluate correlations of anthropometric indicators for identifying IR or IS and determine the cutoff points of the most effective indicators. DESIGN AND SETTING Cross-sectional study in the city of São Paulo. METHODS Sixty-one individuals with normal fasting plasma glucose (NFPG) and 43 overweight women were analyzed. Body mass index (BMI), waist circumference (WC), waist-to-hip ratio, waist-to-height ratio (WHtR), conicity index and the HOMA-IS and HOMA-IR indices were determined. The correlations between the anthropometric indices and IS and IR were determined. ROC analysis was used to determine the areas under the curve (AUC) and cutoff points. RESULTS Among the NFPG individuals, BMI (r = -0.50; P = 0.002) and WHtR (r = -0.45; P = 0.007) showed correlations with HOMA-IS (homeostasis model assessment of insulin sensitivity). The ROC curve demonstrated statistical significance for BMI (AUC = 0.769; P = 0.005), WHtR (AUC = 0.764; P = 0.01) and WC (AUC = 0.702; P = 0.04), and the best cutoff points were 33.3 kg/m², 0.67 and 100 cm, respectively. Among the overweight women, the best correlation with HOMA-IR was demonstrated by WHtR (r = 0.37; P = 0.01), and the best cutoff point was 0.70 (AUC = 0.61; P = 0.25). CONCLUSION The most promising indicators for showing IS among the NFPG individuals were BMI, WHtR and WC. Among the overweight women, WHtR demonstrated greater correlation with IR. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.scielo.br/pdf/spmj/v129n1/v129n1a06.pdf |
| PubMed reference number | 21437506v1 |
| Volume Number | 129 |
| Issue Number | 1 |
| Journal | Sao Paulo medical journal = Revista paulista de medicina |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Area Under Curve Carotid Body Paraganglioma Diabetes Mellitus Evaluation procedure Glucose Insulin Resistance Kilogram Per Square Meter Obesity Overweight P-Value Receiver Operator Characteristics Waist Circumference Waist-Hip Ratio Water consumption insulin, isophane |
| Content Type | Text |
| Resource Type | Article |
