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Robust routes for the synthesis of N-acylated-l-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity
| Content Provider | Semantic Scholar |
|---|---|
| Author | Hodgkinson, James T. Galloway, Warren R. J. D. Casoli, Mariangela Keane, Harriet Su, Xianbin Salmond, George P. C. Welch, Martin Spring, David R. |
| Copyright Year | 2011 |
| Abstract | The ready availability of native quorum sensing molecules and related structural analogues is of significant biological interest in the development of methods to manipulate bacterial quorum sensing systems in a useful fashion. In this Letter we report robust routes for the synthesis of a range of N-acylated-l-homoserine lactone (AHL) quorum sensing molecules. Crucially, we have analysed the enantiopurity of the final AHLs and in all cases, excellent levels were observed. |
| Starting Page | 3291 |
| Ending Page | 3294 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/j.tetlet.2011.04.059 |
| Volume Number | 52 |
| Alternate Webpage(s) | http://www-spring.ch.cam.ac.uk/publications/pdf/2011_TL_3291.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
