Loading...
Please wait, while we are loading the content...
Similar Documents
Ru(II)-polypyridyl surface functionalised gold nanoparticles as DNA targeting supramolecular structures and luminescent cellular imaging agents.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Martínez-Calvo, Miguel Orange, Kim N. Elmes, R. B. P. Poulsen, Bjørn La Cour Williams, D. Clive Gunnlaugsson, Thorfinnur |
| Copyright Year | 2016 |
| Abstract | The development of Ru(II) functionalized gold nanoparticles 1–3·AuNP is described. These systems were found to be mono-disperse with a hydrodynamic radius of ca. 15 nm in water but gave rise to the formation of higher order structures in buffered solution. The interaction of 1–3·AuNP with DNA was also studied by spectroscopic and microscopic methods and suggested the formation of large self-assembly structures in solution. The uptake of 1–3·AuNP by cancer cells was studied using both confocal fluorescence as well as transmission electron microscopy (TEM), with the aim of investigating their potential as tools for cellular biology. These systems displaying a non-toxic profile with favourable photophysical properties may have application across various biological fields including diagnostics and therapeutics. |
| Starting Page | 157 |
| Ending Page | 165 |
| Page Count | 9 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c5/nr/c5nr05598a/c5nr05598a1.pdf |
| PubMed reference number | 26647086v1 |
| Alternate Webpage(s) | https://doi.org/10.1039/c5nr05598a |
| DOI | 10.1039/c5nr05598a |
| Journal | Nanoscale |
| Volume Number | 8 |
| Issue Number | 1 |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Bone structure of radius Buffers Cytology Fluorescence HeLa Cells Hydrodynamics Leukemia, B-Cell Methylene blue Photon Correlation Spectroscopy RPS23 gene RPS28 gene S 27 Therapeutic procedure Transmission Electron Microscopy cellular targeting inorganic phosphate |
| Content Type | Text |
| Resource Type | Article |
