Loading...
Please wait, while we are loading the content...
Similar Documents
Raman spectroscopy monitoring of the cellular activities of a tissue‐engineered ex vivo produced oral mucosal equivalent
| Content Provider | Semantic Scholar |
|---|---|
| Author | Lo, Wen-Liang Feinberg, Stephen E. Izumi, Kenji Chang, Che Shoa Lin, Alan Chiang, Huihua Kenny |
| Copyright Year | 2011 |
| Abstract | Toensurequalitycontrolandassuranceintissueengineering,noninvasive,real-timeandasepticevaluationofcell-baseddevices is required before product release. In this study, Raman spectroscopy was applied to monitor the cellular activities of an oral mucosa equivalent (EVPOME) produced exvivo from cultured autogenous oral keratinocytes and acellular dermis – AlloDerm. Raman spectra showed a positive correlation of the peak area ratio of amide I (1655 cm −1 )/phenylalanine (1004 cm −1 )w ith a negative linear regression (R 2 > 0.95) according to the number of cultured days, especially on the 14thand21st day. This work demonstrates the successful application of Raman spectroscopy for quantitatively monitoring and evaluating the maturity of EVPOME. Copyright c � 2010 John Wiley & Sons, Ltd. |
| Starting Page | 174 |
| Ending Page | 178 |
| Page Count | 5 |
| File Format | PDF HTM / HTML |
| DOI | 10.1002/jrs.2688 |
| Volume Number | 42 |
| Alternate Webpage(s) | https://deepblue.lib.umich.edu/bitstream/handle/2027.42/83170/2688_ftp.pdf;jsessionid=86903F8033F03C785647C9D7DC7E1B98?sequence=1 |
| Alternate Webpage(s) | https://doi.org/10.1002/jrs.2688 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
