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Involvement of P-type Ca2+ channels in the K+- and d-fenfluramine-induced [3H]5-HT release from rat hippocampal synaptosomes
| Content Provider | Semantic Scholar |
|---|---|
| Author | Frittoli, Emanuela Gobbi, Marco Mennini, Tiziana |
| Copyright Year | 1994 |
| Abstract | Abstract The Ca2+-dependent [3H]5-HT release induced by depolarization or by 0.5 μM d-fenfluramine in rat hippocampal synaptosomes, was significantly reduced (35–42%) by three different P-type Ca2+ channels blockers (ω-Agatoxin-IVA, 100 nM, funnel-web spider toxin, FTX, 0.05 μ1/ml, and its synthetic analogue, sFTX, 1 mM), indicating the major role of these channels in the Ca2+ influx preceding neurotransmitter release. |
| Starting Page | 833 |
| Ending Page | 835 |
| Page Count | 3 |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/0028-3908(94)90123-6 |
| Volume Number | 33 |
| Alternate Webpage(s) | https://api.elsevier.com/content/article/pii/0028390894901236 |
| Alternate Webpage(s) | https://www.sciencedirect.com/science/article/pii/0028390894901236?dgcid=api_sd_search-api-endpoint |
| Alternate Webpage(s) | https://doi.org/10.1016/0028-3908%2894%2990123-6 |
| Journal | Neuropharmacology |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |