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Zinc–Nickel Ferrite Nanoparticles as a Contrast Agent in Magnetic Resonance Imaging
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sattarahmady, Naghmeh Heidari, Mina Zare, T. Lotfi, Mehrzad Heli, Hossein |
| Copyright Year | 2016 |
| Abstract | Today, contrast agents are used to improve the sensitivity of magnetic resonance imaging (MRI) to detect pathologic structures. Ferrite nanoparticles are a class of superparamagnetic contrast agents in MRI. In this study, Zn0.5Ni0.5Fe2O4 nanoparticles were synthesized via precipitation method and coated with dextrin to increase the solubility and biocompatibility. The morphology, size, structure, and magnetic properties of nanoparticles were investigated. These nanoparticles have superparamagnetic property with a narrow size distribution with a mean diameter of about 20.5 ± 3.2 nm. MRI study using phantom agar shows that these nanoparticles can be used as an effective contrast agent for T2 and $$T_{2}^{*}$$T2∗-weighted imaging. The relaxivities of r2 and $$r_{2}^{*}$$r2∗ are 8.78 and 82.08 s−1 mmol L−1, respectively. From these findings, it is possible that dextrin-coated Zn0.5Ni0.5Fe2O4 nanoparticles can be used as a good negative contrast agent in MRI. |
| Starting Page | 925 |
| Ending Page | 935 |
| Page Count | 11 |
| File Format | PDF HTM / HTML |
| DOI | 10.1007/s00723-016-0801-9 |
| Volume Number | 47 |
| Alternate Webpage(s) | http://mirc.sums.ac.ir/icarusplus/export/sites/mirc/fa/essay/zincxnickel_ferrite_nanoparticles_as_a_contrast_agent_in_magnetic_resonance_imaging.pdf |
| Alternate Webpage(s) | https://doi.org/10.1007/s00723-016-0801-9 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
