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Rod-Shaped Dextran-Coated Nickel-Ferrite Nanoparticles for Use as Contrast Agents in Magnetic Resonance Imaging
| Content Provider | Semantic Scholar |
|---|---|
| Author | Iqbal, Yusaf Bae, Hongsub Rhee, Ilsu Sungwook |
| Copyright Year | 2018 |
| Abstract | Rod-shaped nickel-ferrite (NiFe2O4) nanoparticles were synthesized using a coprecipitation method and were coated with dextran during the synthesis. Transmission electron microscope (TEM) images showed that the average length and width of these particles were 16.86 nm and 3.92 nm, respectively. The coating status of the dextran on the surface of the particles was confirmed by using Fourier-transform infrared spectroscopy. X-ray diffraction measurements showed that the particles had a spinel crystalline structure. The paramagnetic behavior of the particles provided the contrast effects in magnetic resonance imaging (MRI). The T1 and the T2 relaxivities were 2.05 mM−1·s−1 and 4.92 mM−1·s−1, respectively. The T2 relaxivity was more than twice the T1 relaxivity. However, the T1 relaxivity value was still appropriate for the application of these particles as T1 contrast agents. These findings show that the rod-shaped particles fabricated in this research can be employed as both T1 and T2 MRI contrast agents. |
| Starting Page | 290 |
| Ending Page | 295 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.3938/npsm.68.290 |
| Volume Number | 68 |
| Alternate Webpage(s) | http://pdf.medrang.co.kr/NPSM/2018/068/NPSM068-03-04.pdf |
| Alternate Webpage(s) | https://doi.org/10.3938/npsm.68.290 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |