NDLI: Studies on green synthesized silver nanoparticles using Abelmoschus esculentus (L.) pulp extract having anticancer (in vitro) and antimicrobial applications

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Studies on green synthesized silver nanoparticles using Abelmoschus esculentus (L.) pulp extract having anticancer (in vitro) and antimicrobial applications

Content Provider	Semantic Scholar
Author	Mollick, Masud Rahaman Rana, Dipak Dash, Sandeep Kumar Chattopadhyay, Sourav Bhowmick, Biplab Maity, Dipanwita Mondal, Dibyendu Pattanayak, Sutanuka Roy, Somenath Chakraborty, Mukut Chattopadhyay, Dipankar
Copyright Year	2015
Abstract	Abstract Silver nanoparticles (Ag NPs) were successfully synthesized using AgNO3 via an eco-friendly and simple green route using Abelmoschus esculentus (L.) pulp extract at room temperature. The phytochemicals present in A. esculentus (L.) pulp extract were used both as a reducing and a stabilizing agent for the synthesis of Ag NPs. The stabilization of Ag NPs with phytochemicals was justified using Fourier-transform infrared spectroscopy. The size of the as-synthesized Ag NPs was examined using dynamic light scattering and confirmed by transmission electron microscopy. The crystalline nature of Ag NPs had been identified using X-ray diffraction. The present study demonstrated the efficacy of Ag NPs against Jurkat cells in vitro. Our study also showed that the IC50 dose of Ag NPs leads to the increase in intracellular reactive oxygen species and significantly diminished mitochondrial membrane potential, indicating the effective involvement of apoptosis in cell death. The synthesized Ag NPs also exhibited good antimicrobial activity against different gram class bacteria.
Starting Page	2572
Ending Page	2584
Page Count	13
File Format	PDF HTM / HTML
Volume Number	12
Alternate Webpage(s)	https://core.ac.uk/download/pdf/82124734.pdf
Alternate Webpage(s)	https://doi.org/10.1016/j.arabjc.2015.04.033
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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