NDLI: Immunohistochemical localization of adenosine deaminase (ADA) in primary afferent neurons of the rat

Content Provider	Semantic Scholar
Author	Nagy, James I. LaBella, L. A. Buß, Monika Daddona, Peter E.
Copyright Year	1984
Abstract	Adenosine deaminase (ADA) was detected immunohistochemically in neuronal cell bodies of dorsal root ganglia (DRG) of the rat. ADA-immunoreactivity was confined exclusively to small type B ganglion neurons in cervical, thoracic and lumbar sensory ganglia; large type A neurons in sensory ganglia were devoid of immunostaining for ADA. It was consistently found that only a small proportion of type B neurons in DRG contain immunohistochemically detectable ADA. It is suggested that the expression of high ADA levels is a distinguishing feature of a subpopulation of type B DRG neurons and, further, that ADA in these neurons may reflect their utilization of purines (adenosine or adenine nucleotides) as transmitters or cotransmitters.
File Format	PDF HTM / HTML
DOI	10.1016/0304-3959(84)90345-2
PubMed reference number	6090996
Journal	Medline
Volume Number	18
Alternate Webpage(s)	https://api.elsevier.com/content/article/pii/0304395984903452
Alternate Webpage(s)	https://deepblue.lib.umich.edu/bitstream/handle/2027.42/24752/0000174.pdf?sequence=1
Alternate Webpage(s)	https://deepblue.lib.umich.edu/bitstream/handle/2027.42/24752/0000174.pdf;sequence=1
Alternate Webpage(s)	https://www.sciencedirect.com/science/article/pii/0304395984903452?dgcid=api_sd_search-api-endpoint
Alternate Webpage(s)	https://deepblue.lib.umich.edu/bitstream/handle/2027.42/24752/0000174.pdf?isAllowed=y&sequence=1
Alternate Webpage(s)	https://doi.org/10.1016/0304-3959%2884%2990345-2
Journal	PAIN
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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