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Aporphine alkaloids from Piper erecticaule and acetylcholinesterase inhibitory activity
| Content Provider | Semantic Scholar |
|---|---|
| Author | Salleh, Wan Mohd Nuzul Hakimi Wan Abdullah, Norkamilah Hashim, Nur Athirah Khong, Heng Yen Khamis, Shamsul |
| Copyright Year | 2019 |
| Abstract | Chemical constituents and biological activities of the aerial parts of Piper erecticaule C.DC. have been studied for the first time. Fractionation and purification of the extracts afforded aristolactam AII (1), aristolactam BII (2), piperolactam A (3), piperolactam C (4), piperolactam D (5), together with terpenoids of β-sitosterol, β-sitostenone, taraxerol, and lupeol. The structures of these compounds were obtained by analysis of their spectroscopic data, as well as the comparison with that of reported data. Acetylcholinesterase inhibitory activity revealed that compounds 1 and 3 showed strong AChE inhibitory effects with the percentage inhibition of 75.8% and 74.8%, respectively. |
| Starting Page | 527 |
| Ending Page | 532 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.35588/blacpma.19.18.5.35 |
| Volume Number | 18 |
| Alternate Webpage(s) | https://www.blacpma.usach.cl/sites/blacpma/files/articulo_7_-_1653_-_527_-_532.pdf |
| Alternate Webpage(s) | https://doi.org/10.35588/blacpma.19.18.5.35 |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |