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Nickel-catalyzed anti-Markovnikov hydroarylation of alkenes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc05445b
| Content Provider | Semantic Scholar |
|---|---|
| Author | Nguyen, Julia K. Chong, Andrea Lalic, Gojko |
| Copyright Year | 2019 |
| Abstract | We have developed a nickel-catalyzed hydroarylation of alkenes using aryl halides as coupling partners. Excellent anti-Markovnikov selectivity is achieved with aryl-substituted alkenes and enol ethers. We also show that hydroarylation occurs with alkyl substituted alkenes to yield linear products. Preliminary examination of the reaction mechanism suggests irreversible hydrometallation as the selectivity determining step of the hydroarylation. |
| Starting Page | 3231 |
| Ending Page | 3236 |
| Page Count | 6 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/c8sc05445b |
| PubMed reference number | 30996906 |
| Journal | Medline |
| Volume Number | 10 |
| Alternate Webpage(s) | https://pubs.rsc.org/en/content/articlepdf/2019/sc/c8sc05445b |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c8/sc/c8sc05445b/c8sc05445b1.pdf |
| Alternate Webpage(s) | https://pubs.rsc.org/en/content/articlepdf/2019/sc/c8sc05445b?page=search |
| Alternate Webpage(s) | https://doi.org/10.1039/c8sc05445b |
| Journal | Chemical science |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |