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A multicomponent two-step strategy for the synthesis of polysubstituted pyrrolo[3,2-c]pyridin-4-ones using a solid acid as a recyclable catalyst
| Content Provider | Semantic Scholar |
|---|---|
| Author | Li, Chunmei Zhang, Furen Qi, Chenze |
| Copyright Year | 2019 |
| Abstract | A multicomponent two-step strategy for the synthesis of polysubstituted pyrrolo[3,2-c]pyridin-4-one derivatives has been described. The reactions can be readily performed by mixing inexpensive starting materials using two-step methods under mild conditions, and the products can be easily obtained from the mother liquid without any further treatment. Moreover, the solid acid catalyst can be circulated at least 6 times without obvious deactivation. Furthermore, a mechanism for the reaction process has been proposed. Overall the bond forming efficiency, the use of green solvent as the reaction medium, recyclability of the solid acid catalyst, easy work-up/purification, and a wide substrate scope make this method highly attractive to assemble heterocyclic scaffolds. |
| Starting Page | 3109 |
| Ending Page | 3115 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| DOI | 10.1039/C9GC01120J |
| Volume Number | 21 |
| Alternate Webpage(s) | http://www.rsc.org/suppdata/c9/gc/c9gc01120j/c9gc01120j1.pdf |
| Alternate Webpage(s) | https://doi.org/10.1039/C9GC01120J |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
