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Synthesis of N-alkylpyridin-4-ones and thiazolo[3,2-a]pyridin-5-ones through Pummerer-type reactions.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Huang, Jingjia Hu, Gang An, Shaoyu Chen, Dongding Li, Minglei Li, Pingfan |
| Copyright Year | 2019 |
| Abstract | N-alkylated 4-pyridones were obtained through a one-pot procedure involving either normal or interrupted Pummerer reactions between triflic anhydride activated sulfoxides and 4-fluoropyridine derivatives, followed by hydrolysis. On the other hand, triflic anhydride activated benzyl 6-fluoro-2-pyridyl sulfoxide could react with alkenes or alkynes to afford thiazolo[3,2-a]pyridin-5-ones, via the pyridinium salt intermediates. |
| File Format | PDF HTM / HTML |
| DOI | 10.1021/acs.joc.9b01672 |
| PubMed reference number | 31290663 |
| Journal | Medline |
| Alternate Webpage(s) | https://s3-eu-west-1.amazonaws.com/pstorage-chemrxiv-899408398289/14947121/JOCdraft.pdf |
| Alternate Webpage(s) | https://s3-eu-west-1.amazonaws.com/pstorage-chemrxiv-899408398289/14934350/JOCnote419.pdf |
| Alternate Webpage(s) | https://doi.org/10.1021/acs.joc.9b01672 |
| Journal | The Journal of organic chemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |