NDLI: Neuropharmacological activities of fruit essential oil from Litsea cubeba Persoon

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Neuropharmacological activities of fruit essential oil from Litsea cubeba Persoon

Content Provider	Semantic Scholar
Author	Chen, Chi-Jung Tseng, Yen-Hsueh Chu, Fang-Hua Wen, Tin-Ya Cheng, Wei-Wen Chen, Yu-Ting Tsao, Nai-Wen Wang, Sheng-Yang
Copyright Year	2012
Abstract	Litsea c뺺 (Lauraceae) is woody plant endemic to Taiwan that is traditionally used as a spice. In the current study, several behavioral analyses were performed to evaluate the neuropharmacological activity of the essential fruit oil of L. c뺺 in ICR mice. Oral administration of 100, 300 and 500 mg/kg of L. c뺺 fruit oil significantly prolonged pentobarbitone-induced mouse sleeping time by 20.0, 110.8, and 159.6 %, respectively. In addition, after administration of L. c뺺 oil, mice significantly increased the time spent in the open arms and number of entries into the open arms of an elevated plus maze compared to saline-treated mice suggesting that L. c뺺 oil has anxiolytic activity. A tail-flick test conducted after treatment of mice with 500 mg/kg L. c뺺 fruit oil also suggested that this oil has potent analgetic activity. According to GC/MS analyses, the essential fruit oil of L. c뺺 oil consists of 23 compounds. The main components are geranial (37.16 %), neral (28.29 %), and d-limonene (22.90 %). We conclude that L. c뺺 oil has a potent effect on the central nervous system of mice.
Starting Page	538
Ending Page	543
Page Count	6
File Format	PDF HTM / HTML
DOI	10.1007/s10086-012-1277-3
Volume Number	58
Alternate Webpage(s)	http://for.nchu.edu.tw/up_book/%E7%8E%8B%E5%8D%87%E9%99%BD_201312404371410.1007_s10086-012-1277-3.pdf
Alternate Webpage(s)	https://jwoodscience.springeropen.com/track/pdf/10.1007/s10086-012-1277-3
Alternate Webpage(s)	https://doi.org/10.1007/s10086-012-1277-3
Journal	Journal of Wood Science
Language	English
Access Restriction	Open
Content Type	Text
Resource Type	Article

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