Loading...
Please wait, while we are loading the content...
Similar Documents
Consumption of fructooligosaccharides does not favorably affect blood glucose and serum lipid concentrations in patients with type 2 diabetes.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Alles, Martine S. Roos, Nicole M. De Bakx, J. Carel Lisdonk, E. H. Van De Zock, Peter L. Hautvast, Gilion |
| Copyright Year | 1999 |
| Abstract | BACKGROUND Fructooligosaccharides have been claimed to lower fasting glycemia and serum total cholesterol concentrations, possibly via effects of short-chain fatty acids produced during fermentation. OBJECTIVE We studied the effects of fructooligosaccharides on blood glucose, serum lipids, and serum acetate in 20 patients with type 2 diabetes. DESIGN In a randomized, single-blind, crossover design, patients consumed either glucose as a placebo (4 g/d) or fructooligosaccharides (15 g/d) for 20 d each. Average daily intakes of energy, macronutrients, and dietary fiber were similar with both treatments. RESULTS Compliance, expressed as the proportion of supplements not returned, was near 100% during both treatments. Fructooligosaccharides did not significantly affect fasting concentrations (mmol/L) of serum total cholesterol (95% CI: -0.07, 0.48), HDL cholesterol (-0.04, 0.04), LDL cholesterol (-0.06, 0.34), serum triacylglycerols (-0.21, 0.44), serum free fatty acids (-0.08, 0.04), serum acetate (-0.01, 0.01), or blood glucose (-0.37, 0.40). CONCLUSIONS We conclude that 20 d of dietary supplementation with fructooligosaccharides had no major effect on blood glucose, serum lipids, or serum acetate in patients with type 2 diabetes. This lack of effect was not due to changes in dietary intake, insufficient statistical power, or noncompliance of the patients. |
| Starting Page | 108 |
| Ending Page | 114 |
| Page Count | 7 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://watermark.silverchair.com/64.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAZwwggGYBgkqhkiG9w0BBwagggGJMIIBhQIBADCCAX4GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMIdKZ9ZcT1PYXULGoAgEQgIIBT0zXw4xBzM3kSEer-zJ69xxsPAMTBpRWs8UeZs02lecIaNPgLUL6tHzCu4Zu9As91upFH3p6NtSiWr-JKGwTto_y-uBdjufR3v1j5vRU9H8YvvnTmbPKUPga6dJw3x9oIIhnzbsaNPBNvS3awXjlCA7LVl8lHchuSHi8uzmJEfPEQZnWYNP8C2bjQM-3Kvrp2IshHyOzHuvbBur7Ie2S9xzloLJe5f6BL5rmb3YPm6GdusVAf1DCIYVrttkDDLYIvZvUv-OVek17EXcJu2izR_3Nlv1shB-Pughw8BlhuqU0KCoW5OfS_phCtnrewpt3a8uyRlP81Dvf52DRzIR4Nnzzy21K0oZfU448-zlWMKe_s5E8-eIzgiQYFa4DC39vrzhYiIQeYDjQqS6V0IyqzBPOhd_G5BMJqnJuROjl2MlD9nLG4pDPeSv2rKwLuKxu |
| PubMed reference number | 9925124v1 |
| Volume Number | 69 |
| Issue Number | 1 |
| Journal | The American journal of clinical nutrition |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Acetate Blood Glucose Cholesterol Diabetes Mellitus Diabetes Mellitus, Non-Insulin-Dependent Dietary Fiber Fatty Acids, Volatile Hematological Disease Nonesterified Fatty Acids Patients Triglycerides fructooligosaccharide grams per day millimole |
| Content Type | Text |
| Resource Type | Article |
