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Study of the interaction between novel ruthenium(II)-polypyridyl complexes and calf thymus DNA.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Yang, G. Wu, Jim Zhen Wang, Lingyun Ji, Liang Nian Tian, Xiaojuan |
| Copyright Year | 1997 |
| Abstract | Four new complexes L2RuL'2+, where L = 2,2'-bipyridine (bpy) and 1,10-phenanthroline (phen), L' are Schiff bases or phenylhydrazones derived from 4,5-diazafluoren-9-one (AFO), were prepared. They were characterized by elemental analyses, absorption, IR, and emission spectra. The binding of these complexes to calf thymus DNA has been investigated by absorption, circular dichroism spectroscopy, and viscosity measurement. The experimental results show that the complexes bind to calf thymus DNA by three kinds of binding modes, respectively-electrostatic mode, nonintercalative binding mode, and intercalative binding mode. |
| File Format | PDF HTM / HTML |
| DOI | 10.1016/S0162-0134(96)00194-8 |
| PubMed reference number | 9112762 |
| Journal | Medline |
| Volume Number | 66 |
| Issue Number | 2 |
| Alternate Webpage(s) | http://nathan.instras.com/MyDocsDB/doc-530.pdf |
| Alternate Webpage(s) | https://doi.org/10.1016/S0162-0134%2896%2900194-8 |
| Journal | Journal of inorganic biochemistry |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
