NDLI: Progression of liver fibrosis in monoinfected patients by hepatitis C virus and coinfected by HCV and human immunodeficiency virus.

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Progression of liver fibrosis in monoinfected patients by hepatitis C virus and coinfected by HCV and human immunodeficiency virus.

Content Provider	Semantic Scholar
Author	Tovo, Cristiane Valle Becker, Smile Calisto Da Costa Galperim, Bruno Chaves, Silvia
Copyright Year	2013
Abstract	CONTEXT The progression of liver fibrosis in patients coinfected by hepatitis C virus and human immunodeficiency virus (HCV/HIV) has been increasingly studied in the past decade. Studies made before the highly active antiretroviral therapy suggest that HIV can change the natural history of the HCV infection, leading to a faster progression of the liver fibrosis. OBJECTIVE To evaluate and compare the fibrosis progression in two groups of patients (HCV/HIV coinfected and HCV monoinfected) METHODS Seventy patients HCV monoinfected and 26 patients HCV/HIV coinfected who had not undertaken HCV treatment and were submitted to serial percutaneous liver biopsies were retrospectively evaluated. There was no difference in the fibrosis progression between the two groups. CONCLUSION The fibrosis grade evolution was not worse in the coinfected patients. The immunosuppression absence and the shortest time period between the biopsies in the coinfected group are possible explanations.
Starting Page	19
Ending Page	22
Page Count	4
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://www.scielo.br/pdf/ag/v50n1/0004-2803-ag-50-01-19.pdf
PubMed reference number	23657302v1
Volume Number	50
Issue Number	1
Journal	Arquivos de gastroenterologia
Language	English
Access Restriction	Open
Subject Keyword	Antiretroviral therapy Biopsy Chemical and Drug Induced Liver Injury Fibrosis Fibrosis, Liver HIV Infections Hepatitis A Hepatitis C Antibodies Hepatitis C Virus Infection Immunologic Deficiency Syndromes Natural History Patients Short explanation
Content Type	Text
Resource Type	Article

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