NDLI: Brain stem and cerebellar hyperintense lesions in migraine.

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Brain stem and cerebellar hyperintense lesions in migraine.

Content Provider	Semantic Scholar
Author	Kruit, Mark C. Launer, Lenore J. Ferrari, Michel D. Buchem, Mark A. Van
Copyright Year	2006
Abstract	BACKGROUND AND PURPOSE Migraineurs are at increased risk of cerebellar infarcts and supratentorial white matter lesions. The prevalence, frequency, and distribution of infratentorial hyperintense lesions in migraine are unknown. METHODS Migraineurs with aura (n=161), without aura (n=134), and controls (n=140) from a population-based sample of adults (30 to 60 years of age) were evaluated with MRI. RESULTS Infratentorial hyperintensities were identified in 13 of 295 (4.4%) migraineurs and in 1 of 140 (0.7%) controls (P=0.04). Twelve cases had hyperintensities, mostly bilaterally, in the dorsal basis pontis. Those with infratentorial hyperintensities also had supratentorial white matter lesions more often. CONCLUSIONS We found an increased prevalence of infratentorial (mostly pontine) hyperintensities in migraineurs from the general population. This extends the knowledge about vulnerable brain regions and type of lesions in migraine brains. A hemodynamic ischemic pathogenesis is likely, but further research is needed.
Starting Page	48
Ending Page	55
Page Count	8
File Format	PDF HTM / HTML
Alternate Webpage(s)	http://stroke.ahajournals.org/content/strokeaha/37/4/1109.full.pdf?download=true
Alternate Webpage(s)	http://stroke.ahajournals.org/content/strokeaha/37/4/1109.full.pdf
PubMed reference number	16497982v1
Volume Number	37
Issue Number	4
Journal	Stroke
Language	English
Access Restriction	Open
Subject Keyword	AURKA gene Basis pontis Brain Stem Cerebellar Diseases Cortical Cell Layer of the Cerebellum Hemodynamics Infarction Infratentorial Neoplasms Migraine Disorders Pontine structure White matter Wolff-Parkinson-White Syndrome childhood cerebellar astrocytoma childhood supratentorial ependymoma
Content Type	Text
Resource Type	Article

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