Loading...
Please wait, while we are loading the content...
Similar Documents
Rôle de la conformation des glycoprotéines de l’enveloppe du VIH-1 dans la réponse cytotoxique cellulaire dépendante des anticorps et impact des protéines virales Nef et Vpu
| Content Provider | Semantic Scholar |
|---|---|
| Author | Veillette, Maxime |
| Copyright Year | 2016 |
| Abstract | .............................................................................................................. 40 Introduction ........................................................................................................ 41 Env Glycoproteins Conformation ....................................................................... 42 CD4 induced epitopes in the C1-C2 region of Env as potent ADCC targets: epitope cluster A ................................................................................................. 44 Role of HIV-1 accessory proteins on Env conformational state ........................ 47 Role of easy-to-elicit non-neutralizing antibodies on ADCC responses ............ 49 Methods to measure ADCC: .............................................................................. 51 Defining the enemy: the “Trojan Horse” hypothesis of cell-to-cell HIV transmission ........................................................................................................ 56 Conclusion .......................................................................................................... 64 Acknowledgments .............................................................................................. 64 References .......................................................................................................... 65 CHAPITRE II TECHNIQUES POUR MESURER LES CHANGEMENTS DE CONFORMATION D’ENV ...................................................................................... 80 Introduction ........................................................................................................ 80 CONFORMATIONAL EVALUATION OF HIV-1 TRIMERIC ENVELOPE GLYCOPROTEINS USING A CELL-BASED ELISA ASSAY ................................ 82 Résumé ............................................................................................................... 82 Abstract............................................................................................................... 83.............................................................................................................. 83 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://papyrus.bib.umontreal.ca/xmlui/bitstream/handle/1866/15993/Veillette_Maxime_2016_these.pdf?isAllowed=y&sequence=4 |
| Alternate Webpage(s) | https://microbiologie.umontreal.ca/wp-content/uploads/sites/12/Soutenance_de_these_de_doctorat_MV.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
