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Leukocyte CD15 expression and platelet activation in the coronary sinus after coronary intervention.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Rauch, Ursula Wolff, Ursula Maria Schultheiss, Heinz-Peter Schwimmbeck, Peter Lothar |
| Copyright Year | 2003 |
| Abstract | Markers associated with coronary restenosis must be identified to develop therapeutic strategies for improving the clinical outcome. We studied whether adhesion proteins on leukocytes and platelets from coronary sinus blood were associated with restenosis after coronary intervention in patients with stable coronary artery disease. Adhesion proteins on platelets and leukocytes were measured by flow cytometry. Pre- and postinterventional leukocyte CD15 expression was significantly higher in patients with restenosis than in those without it. Increased leukocyte CD15 expression during the intervention may contribute to coronary restenosis. Inhibition of leukocyte adhesion may be useful for the prevention of restenosis. |
| Starting Page | 10036 |
| Ending Page | 10039 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://www.karger.com/Article/Pdf/73855 |
| PubMed reference number | 14624053v1 |
| Volume Number | 33 |
| Issue Number | 2 |
| Journal | Pathophysiology of haemostasis and thrombosis |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Arteriopathic disease Blood Platelets Coronary Artery Disease Coronary Restenosis Coronary sinus structure Flow Cytometry Leukocytes Nasal sinus Patients Platelet Count measurement Sinus - general anatomical term leukocyte cell-cell adhesion |
| Content Type | Text |
| Resource Type | Article |
