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Caracterização quali-quantitativa de ácido oxálico em espécies medicinais utilizadas no tratamento de diabetes
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sá, Rafaela Damasceno |
| Copyright Year | 2018 |
| Abstract | In the search to increase the success in the treatment of Chronic Noncommunicable Diseases (NCDs), such as diabetes, many patients opt for the indiscriminate use of medicinal plants. Many of these vegetal species are rich in oxalic acid, which can promote renal compromise, accentuating, thus, the metabolic imbalance in these patients. This study aimed to describe the anatomical characteristics of leaf blades of eight plant species used in Brazil for the treatment of diabetes and characterize the morphology, morphometry, identify the sites of accumulation of crystals and their elemental chemical composition, besides to quantify the content of oxalic acid. The species were collected in the metropolitan region of Recife. For the anatomical study, transversal and paraderaml sections were performed, which were analyzed in optical light microscopy, polarization microscopy and scanning electron microscopy. In the histochemistry, different reagents were used to show the metabolites. The microchemical analysis of the crystals was performed by dispersive energy spectroscopy with X-ray detector coupled to a scanning electron microscope. Oxalic acid was determined by titration. The microscopic analysis allowed the identification of the main anatomical characters for the diagnosis of the species. The main types of crystals identified were druses and prismatic crystals. Histochemistry and microchemical analysis showed that, in the eight species, the crystals are of calcium oxalate. The average total oxalate content in the eight species ranged from 3.67 to 6.35 g/100 g dry matter, which is much higher than the oxalate content of daily food. The results obtained contribute to the pharmacobotanical standardization of these species and bring new data in the literature about the oxalic acid content in medicinal plants. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | https://repositorio.ufpe.br/bitstream/123456789/30896/1/TESE%20Rafaela%20Damasceno%20S%C3%A1.pdf |
| Language | English |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
