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Malignant ganglioneuroma arising from mediastinal mixed germ cell tumor.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Chen, Pi-Yu Chen, Winby York-Kwan Ho, Donald Ming-Tak Pan, C. |
| Copyright Year | 2007 |
| Abstract | Mixed germ cell tumors with non-germ cell malignant components rarely occur in the anterior mediastinum. We report a case of a 34-year-old man who presented with an anterior mediastinum mass. Mixed germ cell tumor was initially diagnosed based on the pathologic findings of germinoma on thoracoscopic biopsy and clinical findings of elevated serum alpha-fetoprotein and beta-human chorionic gonadotropin. The patient received preoperative chemotherapy and subsequent complete resection of the residual tumor. Pathologic examination of the excised specimen showed predominantly malignant ganglioneuroma and small residual foci of teratoma. To our knowledge, this is the first reported case of a malignant ganglioneuroma arising from mediastinal mixed germ cell tumor. |
| Starting Page | 20 |
| Ending Page | 23 |
| Page Count | 4 |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://homepage.vghtpe.gov.tw/~jcma/70/2/76.pdf |
| PubMed reference number | 17339149v1 |
| Volume Number | 70 |
| Issue Number | 2 |
| Journal | Journal of the Chinese Medical Association : JCMA |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Anterior mediastinum Chorionic Gonadotropin, beta Subunit, Human Excision Fetal Proteins Ganglioneuroma Germ Cells Germinoma Gonadotropins Human Chorionic Gonadotropin Malignant Childhood Central Nervous System Neoplasm Mixed Germ Cell Tumor Neoplasms Patients Residual Tumor Specimen Teratoma alpha-Fetoproteins |
| Content Type | Text |
| Resource Type | Article |
