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Primary mediastinal non-seminomatous germ cell tumor associated with hemophagocytic syndrome.
| Content Provider | Semantic Scholar |
|---|---|
| Author | Sada, Eriko Shiratsuchi, Motoaki Kiyasu, Junnichi Idutsu, Kensaku Ohtsuka, Rie Nagasawa, Eriko Karube, Kennosuke Takayanagi, Ryoichi Abe, Yasunobu |
| Copyright Year | 2009 |
| Abstract | A 20-year-old man with a primary non-seminomatous mediastinal germ cell tumor (yolk sac tumor and immature teratoma) developed hemophagocytic syndrome (HPS) three months after surgical resection. Around the same time, the patient was found to have bone metastases of the germ cell tumor. No other hereditary or acquired diseases related to HPS were found. The thrombocytopenia was refractory to corticosteroid therapy but improved after chemotherapy performed for germ cell tumor progression. Only three cases of germ cell tumor associated with reactive hemophagocytosis have been previously reported. Successful treatment of the present case by chemotherapy for HPS suggests a close relationship between this rare complication and germ cell tumor. |
| File Format | PDF HTM / HTML |
| Alternate Webpage(s) | http://jsltr.org/journal/49-2/4902_07.pdf |
| PubMed reference number | 19907116v1 |
| Volume Number | 49 |
| Issue Number | 2 |
| Journal | Journal of clinical and experimental hematopathology : JCEH |
| Language | English |
| Access Restriction | Open |
| Subject Keyword | Adrenal Cortex Hormones Excision Hermanski-Pudlak Syndrome Histiocytosis haematophagic Lymphohistiocytosis, Hemophagocytic Mediastinal Germ Cell Tumor Mediastinum Neoplasm Metastasis Neoplasms Patients Steroid therapy Teratoma Teratoma, Malignant Thrombocytopenia Tumor Progression Yolk Sac Tumor bone metastases pediatric intracranial germ cell brain tumor spindle assembly checkpoint |
| Content Type | Text |
| Resource Type | Article |
